Check out the Fly Fishers Place in Sunriver.
http://www.flyfishersplace.com/
They should be able to point you in the right direction. However, here's a couple suggestions:
Metolious - Golden Stones, they cause otherwise PHD trout to make silly decisions!
The Deschutes - Caddis, Warm Springs to Trout Creek - Great Pontoon float, but you need a shuttle.
The Cascade Lakes highway out of Bend - Hosmer, Elk Lake, Lava Lakes, Crane Prairie (hire a guide - tough to figure out on your own), Davis, Black Bass. Trout - Callibaetis and Damsels
East Lake - an hours drive, 3 weeks ago a friend and I caught 50 to 18" in several hours on Chronomids. Damsels and Callibaetis should be popping.
Fall river near Sunriver - PMD's and Caddis. Technical water.
Alder Creek Ranch - Pay for play East of Sisters.
Suttle Lake - West of Sisters - Some big browns.
I got more in my hip pocket.....email if you'd like further details.